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In 2014, Takayama et al. [38] 1st tried to elucidate the in vitro metabolism of ADB-FUBINACA by analysing the metabolites made by the action in the cytochrome P450 enzymes right after one h of incubation with human liver microsomes. Utilizing UPLC/ESI-MS/MS, the authors discovered a single metabolite, ensuing from oxidation with the NConstructive i

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